-Lipoic Acid and Insulin Autoimmune Syndrome  

Oleh:

Ishida, Yoshihiko ; Ohara, Takeshi ; Okuno, Yoko ; Ito, Tatsuo ; Hirota, Yushi ; and Others

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 30 no. 09 (Sep. 2007), page 2240.
Topik: ALA; -lipoic acid ; OGTT; oral glucose tolerance test

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2007.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Insulin autoimmune syndrome, a relatively rare cause of hypoglycemia, is characterized by the production of autoantibodies to insulin in individuals who have not previously been injected with this hormone (1). Drug-induced autoimmunity appears to be important in the pathogenesis of this syndrome, given that 50% of affected individuals have taken certain drugs, most of which (such as methimazole, -mercaptopropionyl glycine, or glutathione) contain the sulfydryl group, before its onset (1). We now report a case of insulin autoimmune syndrome likely induced by -lipoic acid (ALA), a reduced form of which contains the sulfydryl group (2)......

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