Using a combination inhaler (budesonide plus formoterol) as rescue therapy improves asthma control  

Oleh:

Barnes, Peter J.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: British Medical Journal (keterangan: ada di Proquest) vol. 335 no. 7618 (Sep. 2007), page 513.
Topik: Practice

Ketersediaan

Perpustakaan FK Nomor Panggil: B16.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

The clinical problem Asthma is one of the commonest chronic diseases worldwide and is effectively controlled in most patients with maintenance treatment. In those with moderate or severe persistent asthma, control may be achieved with an inhaled corticosteroid or a combination inhaler containing a corticosteroid and a long acting 2 agonist. The combination inhaler is more effective, but patients still require short acting 2 agonists such as salbutamol or terbutaline to relieve symptoms. I describe a new approach for acute exacerbation—SMART (single inhaler maintenance and reliever therapy). This uses the combination inhaler, rather than the short acting 2 agonist, as the reliever. The evidence for change Using a formulation of budesonide plus formoterol (budesonide/formoterol) both as a reliever and as maintenance therapy once or twice daily is more effective in controlling asthma than conventional approaches using budesonide/formoterol, fluticasone/salmeterol, or high dose corticosteroids (budesonide or fluticasone) as the maintenance treatment with short acting 2 agonists as relievers (table).1 2 3 4 5 The most striking . . .

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