Inherited thrombophilia and pregnancy associated venous thromboembolism  

Oleh:

Lim, Wendy ; Eikelboom, John W. ; Ginsberg, Jeffrey S.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: British Medical Journal (keterangan: ada di Proquest) vol. 334 no. 7607 (Jun. 2007), page 1318.

Ketersediaan

Perpustakaan FK Nomor Panggil: B16.K.2007.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Introduction Pulmonary embolism is the leading cause of maternal mortality in developed countries and accounts for 20% of pregnancy related deaths in the United States.1 2 The risk of pulmonary embolism and deep vein thrombosis, collectively known as venous thromboembolism, is increased during pregnancy and is further increased by the presence of inherited or acquired thrombophilias. We summarise the epidemiology and diagnosis of venous thromboembolism in pregnancy and discuss the anticoagulant management of women with inherited thrombophilia who are at risk of, or who develop, venous thromboembolism during pregnancy and the postpartum periodA 30 year old woman, a known heterozygote for the factor V Leiden mutation, presents at eight weeks' gestation in her first pregnancy wondering whether she should receive prophylactic anticoagulation to prevent recurrent venous thrombosis during pregnancy. Several years ago she developed a deep vein thrombosis of the left leg after an ankle fracture and prolonged immobilisation and was . . .

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