Intrapartum and Postpartum Analgesia for Women Maintained on Methadone During Pregnancy  

Oleh:

Meyer, Marjorie ; Wagner, Katherine ; Benvenuto, Anna ; Plante, Dawn ; Howard, Diantha

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Obstetrics and Gynecology vol. 110 no. 02 (Aug. 2007), page 261.

Ketersediaan

Perpustakaan FK Nomor Panggil: O01.K.2007.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

OBJECTIVE: To determine whether methadone maintenance alters intrapartum or postpartum pain or medication requirements. METHODS: Sixty-eight patients treated with methadone for opiate dependence during pregnancy (vaginal n=35; cesarean n=33) were matched retrospectively to control women. Analgesic medication and pain scores (0–10) were extracted from the medical record. The primary endpoint was opiate use postpartum (oxycodone equivalents). The secondary endpoints were pain scores and intrapartum analgesia. RESULTS: There were no differences in intrapartum pain or analgesia. After vaginal birth, methadone-maintained women experienced increased pain (methadone, 2.7 [1.9–5.0]; control, 1.4 [0.5–3.0], P=.001) but no increase in opiate use ([mean±standard deviation] methadone 12.7±32.1; control 6.8±12.7 mg/24 h, P=.33); after cesarean delivery both pain (methadone, 5.3 [4.1–6.0]; control, 3.0 [2.2–3.9], P=.001) and opiate use (methadone, 91.6±51.8; control, 54.0±18.6 mg/24 h, P=.001) increased. CONCLUSION: Methadone-maintained women have similar analgesic needs and response during labor, but require 70% more opiate analgesic after cesarean delivery.

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