Mist Delivery of Eye Medication to the Anterior Segment  

Oleh:

Collins, James F. ; Dartt, Darlene A ; Dana, Reza

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: American Journal of Ophthalmology (keterangan: ada di ClinicalKey) vol. 144 no. 01 (Jul. 2007), page 137.

Ketersediaan

Perpustakaan FK Nomor Panggil: A12.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Purpose To compare the mydriatic efficacies of mist and drop delivery of tropicamide 1.0%. Design Randomized, masked, active, controlled clinical trial. Methods One hundred subjects were randomized to receive small-volume (6 µl) mist administration of tropicamide 1.0% in one eye and either nothing or a conventional drop (30 µl) of the same solution in the fellow eye. Results Comparing misted eyes with untreated eyes in the same subjects, the mean maximal increase in pupil diameter in the misted eyes was 2.02 mm and was 0.25 mm in the fellow eyes. The difference is statistically significant (P = .001) Comparing mist-treated eyes with drop-treated eyes in the same subjects, the mean maximal increase in pupil diameter in the misted eyes was 1.98 mm and was 2.11 mm in the drop-treated eyes. The difference was not statistically significant (P = .051). Conclusions Small-volume mist and conventional drop delivery of tropicamide 1.0% were shown to be similar in mydriatic effectiveness.

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