Detail Regulation of Drosophila Life Span by Olfaction and Food-Derived Odors   Oleh:  Libert, Sergiy ; Zwiener, Jessica ; Chu, Xiaowen ; VanVoorhies, Wayne ; Roman, Gregg ; Pletcher, Scott D. Jenis: Article from Bulletin/Magazine Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 315 no. 5815 (Feb. 2007), page 1133. Topik: Physiology Ketersediaan Perpustakaan FK Nomor Panggil: S01.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel Smell is an ancient sensory system present in organisms from bacteria to humans. In the nematode Caeonorhabditis elegans, gustatory and olfactory neurons regulate aging and longevity. Using the fruit fly, Drosophila melanogaster, we showed that exposure to nutrient derived odorants can modulate life span and partially reverse the longevity-extending effects of dietary restriction. Furthermore, mutation of odorant receptor Or 83b resulted in severe olfactory defects, altered adult metabolism, enhanced stress resistance, and extended life span. Our findings indicate that olfaction affects adult physiology and aging in Drosophila, possibly through the perceived availability of nutritional resources, and that olfactory regulation of life span is evolutionarily conserved. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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