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Nuclear Activity of MLA Immune Receptors links Isolate-Specific and Basal Disease-Resistance Responses
Oleh:
Shen, Qian-Hua
;
Saijo, Yusuke
;
Mauch, Stefan
;
Biskup, Christoph
;
Bieri, Stephane
;
Keller, Beat
;
Seki, Hikaru
;
Ulker, Bekir
;
Somssich, Imre E.
;
Schulze-Lefert, Paul
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
SCIENCE (keterangan: ada di Proquest) vol. 315 no. 5815 (Feb. 2007)
,
page 1098.
Topik:
Plant Science
Ketersediaan
Perpustakaan FK
Nomor Panggil:
S01.K.2007.02
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Plant immune responses are triggered by pattern recognition receptors that detect conserved pathogen-associated molecular patterns (PAMPs) or by resistance (R) proteins recognizing isolate specific pathogen effectors. We show that in barley, intracellular mildew A (MLA) R proteins function in the nucleus to confer resistance against the powdery mildew fungus. Recognition of the fungal avirulence AlO effector by MLAIO induces nuclear associations between receptor and WRKY transcription factors. The identified WRKY proteins act as repressors of PAMP-triggered basal defense. MLA appears to interfere with the WRKY repressor function, thereby de-repressing PAMPtriggered basal defense. Our findings reveal a mechanism by which these polymorphic immune receptors integrate distinct pathogen signals.
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