Redarkening of Port-Wine Stains 10 Years after Pulsed-Dye-Laser Treatment  

Oleh:

Huikeshoven, Menno ; Koster, Petra H.L ; Borgie, Corianne A.j.M De ; Beek, Johan F ; Gemert, Martin J.C. Van ; Horst, Chantal M.A.M. Van Der

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 356 no. 12 (Mar. 2007), page 1235.

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Perpustakaan FK Nomor Panggil: N08.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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BACKGROUND Although pulsed-dye-Iaser therapy is currently the gold standard for the treatment of port-wine stains, few objective data are available on its long-term efficacy. Using 5 objective color measurements, we performed a 10-year follow-up of a previously conducted prospective clinical study of the treatment of port-wine stains with a pulsed-dye laser. METHODS We invited the patients to undergo repeated color measurements performed by the same procedures as in the previous study. The results at long-term follow-up were compared with color measurements obtained before treatment and after comple- 9 tion of an average of five laser treatments of the complete port-wine stain. A ques- C tionnaire was used to investigate patients' satisfaction with the treatment and their perception of long-term changes in the stain. RESULTS Of the 89 patients from whom color measurements were obtained in the previous study, 51 were included in this study. The patients had received a median of seven additional treatment sessions since the last color measurement, which had been made after an average of five treatments. The median length of follow-up was 9.5 years. On average, the stain when measured at follow-up was significantly darker than it was when measured after the last of the initial five laser treatments (P=O.OOl), but it was still significantly lighter than it was when measured before treatment (P

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